This flashcard describes the mechanism of ETEC's heat-stable toxin (ST), which activates guanylate cyclase, increasing cGMP and inhibiting sodium/chloride absorption in the small intestine, leading to watery diarrhea (FA mnemonic).
La flashcard décrit le mécanisme de la toxine thermostable (ST) de l'ETEC, qui active la guanylate cyclase, augmentant le GMPc et inhibant l'absorption de sodium et de chlorure dans l'intestin grêle, entraînant une diarrhée aqueuse (FA mnemonic).
| Front | Bugs with exotoxins: Bacteria that increase fluid secretion: Enterotoxigenic E Coli (ETEC) Toxin: Heat-stable toxin (ST) mechanism: ____activates?1 (increase in?1) --> two absorptive changes (and location?) Manifestation: 1 (FA mnemonic) |
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