The flashcard details Vibrio cholerae, its cholera toxin that activates adenylate cyclase via an alpha subunit, increasing cAMP and chloride/bicarbonate secretion in the small intestine, causing watery diarrhea ("rice-water stool"), and is an AB toxin.
La flashcard détaille le Vibrio cholerae, sa toxine cholérique qui active l'adénylate cyclase via une sous-unité alpha, augmentant l'AMPc et la sécrétion de chlorure et de bicarbonate dans l'intestin grêle, entraînant une diarrhée aqueuse ("rice-water stool"), et est une toxine de type AB.
| Front | Bugs with exotoxins: Bacteria that increase fluid secretion: Vibrio cholerae Toxin: 1 Mechanism: ___activates?1 (increase?1) how? --> two secretory effects (and where?) Manifestation: 1 AB toxin or no? |
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