This flashcard details Bordatella pertussis, its pertussis toxin (PT) which inhibits adenylyl cyclase by inactivating the Gi protein, leading to increased cAMP. It also impairs phagocytic function and causes whooping cough.
Cette flashcard détaille la Bordatella pertussis, sa toxine pertussique (PT) qui inhibe la désignation adényl cyclase en désactivant la protéine Gi, entraînant une augmentation de l'AMPc. Elle altère également la fonction phagocytaire et conduit à la coqueluche.
| Front | Bugs with exotoxins: Inhibit phagocytic ability Bordatella pertussis Toxin: 1 mechanism: ___activates?1 how? 1 other MOA manifestation: 1 main (what is seen in this symptom?2) is the toxin the cause? what can occur in adults? AB toxin or no? |
|---|---|
| Back |
Learn with these flashcards. Click next, previous, or up to navigate to more flashcards for this subject.
Next card: Bugs exotoxins inhibit neurotransmitter release
Previous card: Bugs exotoxins bacteria increase fluid secretion vibrio cholerae
Up to card list: Microbiology COMPLETE First Aid 2016 Deck Yieldski