Prion diseases are caused by the conversion of normal (predominantly alpha-helical) prion protein (PrPc) to a transmissible beta-pleated form (PrPsc), transmitted via CNS-related tissue (iatrogenic CJD) or food contaminated by BSE-infected animal products (variant CJD).
朊病毒病是由正常（主要是α螺旋結構）的朊病毒蛋白（PrPc）轉化為傳染性的β折疊結構形式（PrPsc）引起的。通過接觸CNS相關組織（醫源性CJD）或被 BSE感染的動物產品污染的食物（變異型CJD）傳播。
| Front | Prion diseases are caused by the conversion of a normal (predominantly ____ - ____ ) protein termed prion protein ( ____ ) to a ____ - ____ form ( ____ ), which is transmissible via CNS-related tissue ( ________ ____ ) or ____ contaminated by ____ -infected animal products ( ____ ____ ). |
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| Back | Prion diseases are caused by the conversion of a normal (predominantly α-helical) protein termed prion protein (PrPc) to a β-pleated form (PrPsc), which is transmissible via CNS-related tissue (iatrogenic CJD) or food contaminated by BSE-infected animal products (variant CJD). Bovine spongiform encephalopathy (BSE) |
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