Front | Prion diseases are caused by the conversion of a normal (predominantly ____ - ____ ) protein termed prion protein ( ____ ) to a ____ - ____ form ( ____ ), which is transmissible via CNS-related tissue ( ________ ____ ) or ____ contaminated by ____ -infected animal products ( ____ ____ ). |
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Back | Prion diseases are caused by the conversion of a normal (predominantly α-helical) protein termed prion protein (PrPc) to a β-pleated form (PrPsc), which is transmissible via CNS-related tissue (iatrogenic CJD) or food contaminated by BSE-infected animal products (variant CJD). Bovine spongiform encephalopathy (BSE) |
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