PrPsc resists protease degradation and facilitates the conversion of more PrPc to PrPsc. It is resistant to standard sterilization methods, including autoclaving, and its accumulation leads to spongiform encephalopathy, dementia, ataxia, and death.
PrPsc抵抗蛋白酶降解，並促進更多PrPc轉化為PrPsc。它對標準滅菌方法（包括標準高壓滅菌）具有抵抗力，其積聚會導致海綿狀腦病、癡呆、共濟失調和死亡。
| Front | Prions PrPsc resists ________ ________ and facilitates the conversion of still more ____ to ____ . Resistant to standard sterilizing procedures, including standard ________. Accumulation of PrPsc results in ________ ________ A and ________, ________, and death. |
|---|---|
| Back | PrPsc resists protease degradation and facilitates the conversion of still more PrPc to PrPsc. Resistant to standard sterilizing procedures, including standard autoclaving. Accumulation of PrPsc results in spongiform encephalopathy A and dementia, ataxia, and death. |
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