Question

CGD patients are susceptible to what organisms?

Accepted Answer

Catalase (+) organisms → bacteria excrete H2O2 into cell environment → myeloperoxidase can convert this bacterial H2O2 → HOCL- (bleach) to KILL bacteria → however, many bacteria have their own catalase, which breask down their own H2O2 so that there is not enough H2O2 to convert into HOCL- (bleach)

Front	CGD patients are susceptible to what organisms?
Back	Catalase (+) organisms → bacteria excrete H₂O₂ into cell environment → myeloperoxidase can convert this bacterial H₂O₂ → HOCL^- (bleach) to KILL bacteria → however, many bacteria have their own catalase, which breask down their own H₂O₂ so that there is not enough H₂O₂ to convert into HOCL^-(bleach)

H O Bacteria Catalase Convert Hocl Bleach Cgd