| Front | (3) viruses associated with cancer → associated mechanisms? |
|---|---|
| Back | ALL cancer-causing viruses are DNA viruses (except HCV) → HBV | HPV | EBV → cell proliferation with excess DNA nucleotide synthesis in S phase → HBV has strong association with HCC HPV produces E6 viral protein which ↓Rb and E7 viral protein which ↓p53, which kicks cell cycle into overdrive and leads to overproliferation | overgrowth of epithelial cells, dysplasia, and ultimately cervical cancer EBV is associated with Burkitt lymphoma (B-lymphocyte lymphoma), which manifests as B cell proliferation, and Nasopharyngeal carcinoma. The t(8;14) translocation is consistently associated with Burkitt lymphoma, but this translocation alone is not found in nasopharyngeal carcinoma. ↓ Burkitt lymphoma Nasopharyngeal carcinoma Oral hairy leukoplakia |
Tags: microbiology
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