Histoplasmosis, found in the Mississippi and Ohio River valleys and associated with bird/bat droppings, is characterized by yeast forms within macrophages. It can cause pancytopenia, oral ulcers, and splenomegaly, diagnosed by urine or serum antigen tests.
Histoplasmosis es un hongo que se encuentra en los valles de los ríos Mississippi y Ohio, asociado con excrementos de pájaros y murciélagos. Se caracteriza por levaduras dentro de macrófagos y puede causar pancitopenia, úlceras palatinas/linguales y esplenomegalia. El diagnóstico se realiza midiendo antígenos en orina o suero.
| Front | Histoplasmosis Location Key Histologic feature Vectors Manifestations Diagnosis |
|---|---|
| Back | Location ↓ Mississippi and Ohio River Valleys Features ↓ Macrophage filled with Histoplasma yeasts "Histo hides in macrophages" Source ↓ Bird droppings (starlings) | bat droppings Manifestations ↓ Pancytopenia Palatal ulcers | Tongue ulcers Splenomegaly Diagnosis ↓ Urine Ag | Serum Ag |
Tags: microbiology
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