Nystatin forms membrane pores by binding to ergosterol, causing ion and water leakage, and is used for localized fungal infections like oral thrush, diaper rash, and vaginal candidiasis.
Nistatin formira pore u ćelijskoj membrani vezivanjem za ergosterol, što dovodi do curenja jona i vode, i koristi se za lokalne gljivične infekcije poput oralne kandidijaze, pelenskog osipa i vaginalne kandidijaze.
| Front | Nystatin → MOA → (2) uses |
|---|---|
| Back | Forms membrane pores in ergosterol so that Na+ | K+ leak out and H2O follows → local fungal infections (oral thrush | diaper rash) → vaginal candidiasis |
Tags: antifungal, drugs
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