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Polio Vaccine Salk Sabin Booster  Vs Major Differences

Front Salk® vs. Sabin® polio vaccines

What are the major differences?
Back

Salk®
Killed viral vaccines
Inactivated Polio Vaccine (IPV)
IM injection
Require booster

vs.

Sabin®
Live attenuated vaccine

Oral Polio Vaccine (OPV)

↑mucosal IgA interrupts mucosal transmission
(feco-oral route)

Better immune response 
(humoral|CMI)

Can revert back to wild type virus

Requires no booster

Tags: microbiology

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