| Front | What reverse transcriptase inhibitors work by directly binding the reverse transcriptase enzyme? |
|---|---|
| Back | NNRTIs → original genetic information from HIV is in the form of RNA and reverse transcriptase is needed to convert ssRNA to dsDNA → two classes of reverse transcriptase inhibitors → Non-Nucleoside Reverse Transcriptase Inhibitors (nevirapine) which bind enzyme directly to block catalytic site → Nucleoside analogue Reverse Transcriptase Inhibitors (zidovudine) which are incorporated into DNA strand to prevent elongation |
Tags: antiviral, drugs
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