Bordetella Pertussis virulence involves toxins that increase cAMP, leading to increased mucus secretion and diarrhea in the throat, alongside pertussis toxin and filamentous hemagglutinin that attach to human cilia.
La virulencia de Bordetella Pertussis se debe a la toxina que aumenta el cAMP, provocando secreción de mucosidad y "diarrea" en la garganta, además de la toxina pertussis y la hemaglutinina filamentosa que se unen a los cilios humanos.
| Front | Bordetella Pertussis Virulence |
|---|---|
| Back | Increase mucous secretion in the throat Toxin--> increase cAMP-->increase water secretion (diarrhea in the throat) - Pertussis Toxin (A-B subunit) -->Attachment to human cilia (block cilia movement) --> Increase mucus secretion (increase cAMP levels) - Filamentous Hemagglutinin --> Attachment to human cilia |
Tags: plasmid
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