ATP is crucial for muscle contraction by detaching myosin from actin, resetting the myosin head, and powering the muscle contraction after cross-bridge formation.
ATP's role in muscle contraction includes breaking cross-bridges, recocking the myosin head after hydrolysis, and releasing ADP/Pi during the power stroke.
| Front | Role of ATP in muscle contraction |
|---|---|
| Back | • Binding of ATP to myosin: causes the breakdown of the cross-bridges • Hydrolysis of ATP into ADP & Pi: causes the recocking of myosin head (returns it from bent state to straight) • Release of ADP & Pi from myosin: occurs after formation of new crossbridge, during the powerstroke |
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