Neurotransmitter release involves nerve impulses reaching the synaptic knob, opening calcium channels, and Ca ion influx promoting synaptic vesicle fusion and exocytosis.
To release neurotransmitters, a nerve impulse reaches the synaptic knob, opening calcium channels. Inflowing Ca ions trigger synaptic vesicles to fuse with the membrane and release their contents.
| Front | Proces of release of neurotransmitter from axon |
|---|---|
| Back | • Nerve impulse arrives at synaptic knob. • Calcium channels open in the presynaptic membrane. • Ca ions rush into the axon, causing synaptic vesicles to move towards the membrane. • The vesicles fuse with the membrane and are released. |
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