Precursor enzymes can be activated by the addition of a cofactor (forming a holoenzyme), by another enzyme, or by a change in conditions like pH.
Precursor enzymes can be activated by the addition of a cofactor (forming a holoenzyme), by another enzyme, or by a change in conditions like pH.
| Front | How precursor enzymes activate 2.1.4(f) |
|---|---|
| Back | - often require change in TS - done in a few ways: - addition of cofactor (precursor enzyme called apoenzyme before addition and holoenzyme after addition while activated), this cofactor usually is shape of active site - done by another enzyme - by change of conditions (changes TS which activated it), these precursor enzymes called proenzymes/ zymogens |
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