DNA replication involves DNA helicase unzipping the strand, followed by DNA polymerase catalyzing the formation of phosphodiester bonds between complementary free nucleotides, resulting in two identical DNA molecules (semi-conservative replication).
DNA replication involves DNA helicase unzipping the strand, followed by DNA polymerase catalyzing the formation of phosphodiester bonds between complementary free nucleotides, resulting in two identical DNA molecules (semi-conservative replication).
| Front | DNA replication 2.1.3(e) |
|---|---|
| Back | - DNA strand unzips due to DNA helicase travelling along backbone catalysing reactions to break H2 bonds - once fully unzipped, free DNA nucleotides pair complementarily to the exposed base pairs - DNA polymerase then catalyses reactions forming phosphodiester bonds within free DNA nucleotides, forming PO4 backbone - called semi-conservative as for each helix, one of the strands were part of the original copy |
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