The induced-fit hypothesis suggests that substrate binding causes a temporary change in the enzyme's tertiary structure, straining the substrate to lower activation energy.
The induced-fit hypothesis suggests that substrate binding causes a temporary change in the enzyme's tertiary structure, straining the substrate to lower activation energy.
| Front | Induced fit hypothesis 2.1.4(c) |
|---|---|
| Back | - initial interaction with enzyme and substrate relatively weak but these induce changes in tertiary structure of enzyme - strains substrate, weakening bonds in it lowering activation energy - active site changes shape slightly and not complementary to substrate, but returns after reaction |
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