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OCR A Biology

Mrna Bind Translation Translational Control Stop Degrade Inhibitory

Translational control mechanisms include degrading mRNA, blocking mRNA binding to ribosomes, activating initiation factors to start translation, or modifying enzymes through phosphorylation.

Translational control halts or initiates protein synthesis by mechanisms such as mRNA degradation, binding of inhibitory proteins to mRNA, activation of initiation factors, or enzyme phosphorylation mediated by protein kinases.

Front Translational control
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  • stop translation
    • degrade mRNA
    • Inhibitory proteins bind to mRNA so it cant bind to ribosomes
  • start translation
    • activate initiation factors which allow mRNA to bind to ribosome
    • protein kinases catalyse phosphorylation of enzyme (so it activates as it changes TS), and they themselves are activated by cAMP

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