Upon reaching the SR, the action potential stimulates Ca2+ channels to open, releasing Ca2+ into the sarcoplasm. Ca2+ binds to troponin, shifting tropomyosin off the actin binding site, allowing actin-myosin cross-bridge formation and muscle contraction.
Una vez que el potencial de acción alcanza el SPR, se abren los canales de Ca2+, liberando Ca2+ en el sarcoplasma. El Ca2+ se une a la troponina, desplazando la tropomiosina del sitio de unión de la actina, lo que permite la formación de puentes de actina-miosina y la contracción muscular.
| Front | myosin filaments |
|---|---|
| Back | have globular heads whihc have binding sites for ATP and actin, tails align with eachother to form myosin filaments |
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