Changes in pH affect the ionization of R groups, disrupting hydrogen and ionic bonds and altering the enzyme's tertiary structure, with an optimum pH range where activity is highest.
Changes in pH affect the ionization of R groups, disrupting hydrogen and ionic bonds and altering the enzyme's tertiary structure, with an optimum pH range where activity is highest.
| Front | Interaction of H+ with R groups 2.1.4(d) |
|---|---|
| Back | - H+ interacts with polar R groups so changing conc of H+ affects the interaction and interaction between R groups - more H+, less R groups able to interact with each other, bonds break and shape changes - less H+, more R groups interact, bonds form and shape changes - therefore narrow range called optimum pH |
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