| Front | Sickle cell anaemia is an inherited disorder in which haemoglobin crystallises when the partial pressure of oxygen (pO2) is low. The red blood cells change shape and oxygen transport is disrupted. Treatment with drugs, such as hydroxyurea, can stimulate adults to produce fetal haemoglobin rather than adult haemoglobin. Suggest why this treatment might be of benefit to adults with sickle cell anaemia. |
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| Back | fetal Hb can pick up more O2 at low pO2 |
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