Question

What is a Schwannoma and what does it look like on histology?

Accepted Answer

● Encapsulated, benign tumor that arises from Schwann cells
● Rarely transforms into a malignant tumor
● Histology: Biphasic pattern
○ Antoni A: nuclear palisading; spindle cells arrange in
interlacing cords, whorls, or palisades that form verocay
bodies (*)

○ Antoni B: loose myxoid association of cells; stellate cells that have
mucous stroma

Front	What is a Schwannoma and what does it look like on histology?
Back	● Encapsulated, benign tumor that arises from Schwann cells ● Rarely transforms into a malignant tumor ● Histology: Biphasic pattern ○ Antoni A: nuclear palisading; spindle cells arrange in interlacing cords, whorls, or palisades that form verocay bodies (*) ○ Antoni B: loose myxoid association of cells; stellate cells that have mucous stroma

Cells Tumor Antoni Schwannoma Histology Encapsulated Benign Arises