| Front | What is Meesmann corneal dystrophy? What does histology show? What are the genetic associations? |
|---|---|
| Back | ● Epithelial corneal dystrophy that shows punctate, blister-like, round to oval opacities within the corneal epithelium, best seen on retroillumination ● Typically presents early in life with mild foreign body sensation and slight decreased visual acuity ● Histology shows coarse basement membrane, fibrillogranular material within epithelial cells and cysts = “peculiar substance” ● Mutations of KRT3 or KRT12 ● Autosomal dominant inheritance |
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