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Seborrheic Appearance Cysts Keratosis Circumscribed Oval Dome Shaped

Front What is a seborrheic keratosis and what can it be associated with?
Back ● Well circumscribed, oval, dome shaped to verrucous benign papillomatous proliferation of basal cells within epidermis ● Usually pink or brown in color ● “Stuck-on” appearance ● Lesions have cystic collections of keratin ● Pathology shows pseudohorn cysts or cysts line with acanthotic stratified epithelium ● Sudden appearance of multiple seborrheic keratoses = Leser-Trelat sign which is associated with GI adenocarcinoma

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