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Dht Underlying Pathlogy Benign Prostatic Hyperplasia Bph Testosterone

Text What is the underlying pathlogy behind Benign Prostatic Hyperplasia (BPH)?

Testosterone is converted to DHT (dihydrotestosterone) by 5-alpha-reductase in stromal cells

DHT acts on androgen receptors of stromal/epithelial cells, causing formation of hyperplastic nodules

Tags: pathoma_ch.14_male_genital_prostate

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