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A-Level Biology OCR A

Active Substrate Enzyme Competetive Inhibitor Rate Site Molecules

Competitive inhibitors, similar in shape to substrates, bind to active sites, blocking substrate access and reducing reaction rate.

Competitive inhibitors, with shapes similar to the substrate, bind to the active site, blocking substrate access and slowing the reaction rate.

Front Explain how a competetive inhibitor affects the rate of an enzyme-controlled reaction.
Back Effect of competetive inhibitors:
  • Molecule/part of molecule with similar shape to substrate fits into the active site of the enzyme
  • This blocks substrate from entering active site, preventing enzyme from catalysing
  • Enzyme cant carry out its function - inhibited
  • Substrate and inhibitor molecules will compete to bind to active sites
  • Number of molecules binding to active site in given time reduced, rate of reaction slowed

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