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A-Level Biology OCR A

Irreversible Inhibitor Enzyme Define Dissociate Ease Permanently Disabling

Irreversible inhibitors bind covalently, permanently disabling the enzyme and are not reversed by increasing substrate concentration.

Irreversible inhibitors bind covalently and permanently disable the enzyme, and their effects cannot be reversed by increasing substrate concentration.

Front Define irreversible inhibitor.
Back Irreversible inhibitor - inhibitor that cannot dissociate from the enzyme with ease, permanently disabling the enzyme (binds covalently)
  • Some competetive inhibitors
  • All non-competetive inhibitors
  • Their effect cannot be reversed by increasing substrate concentration

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