Question

State where M checkpoint occurs, what is checked at the checkpoint and what happens if cell passes/fails.

Accepted Answer

M checkpoint (spindle assembly checkpoint) - during metaphase of mitosisChecks if all chromatids are correctly attached to spindle fibersIf requirements satisfied - cell continues with mitosisIf requirements not satisfied - mitosis paused, repair attempted

Front	State where M checkpoint occurs, what is checked at the checkpoint and what happens if cell passes/fails.
Back	M checkpoint (spindle assembly checkpoint) - during metaphase of mitosis Checks if all chromatids are correctly attached to spindle fibers If requirements satisfied - cell continues with mitosis If requirements not satisfied - mitosis paused, repair attempted

Checkpoint Mitosis M Cell Requirements Satisfied State Occurs