Question

State where G2 checkpoint occurs, what is checked at the checkpoint and what happens if cell passes/fails.

Accepted Answer

G2 checkpoint - at the end of G2 before start of mitotic phaseChecks: cell size, DNA replication, DNA damageIf requirements satisfied - molecular processes that signal beginning of mitosis initiatedIf requiremetns not satisfied - cell pauses at G2 to try and repair, if irreparable cell undergoes apoptosis

Front	State where G2 checkpoint occurs, what is checked at the checkpoint and what happens if cell passes/fails.
Back	G2 checkpoint - at the end of G2 before start of mitotic phase Checks: cell size, DNA replication, DNA damage If requirements satisfied - molecular processes that signal beginning of mitosis initiated If requiremetns not satisfied - cell pauses at G2 to try and repair, if irreparable cell undergoes apoptosis

G2 Cell Checkpoint Dna Satisfied State Occurs Checked