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A-Level Biology OCR A

G2 Cell Checkpoint Dna Satisfied State Occurs Checked

The G2 checkpoint verifies cell size, DNA replication, and damage before mitosis; failure prompts repair or apoptosis if damage is irreversible.

The G2 checkpoint, at the end of G2, checks cell size, DNA replication, and damage; passing initiates mitosis, while failure leads to repair or apoptosis if irreparable.

Front State where G2 checkpoint occurs, what is checked at the checkpoint and what happens if cell passes/fails.
Back
G2 checkpoint - at the end of G2 before start of mitotic phase
  • Checks: cell size, DNA replication, DNA damage
  • If requirements satisfied - molecular processes that signal beginning of mitosis initiated
  • If requiremetns not satisfied - cell pauses at G2 to try and repair, if irreparable cell undergoes apoptosis

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