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Enzyme Increasing Bonds Protein Structure Changed Shape Longer

Temperatures above the optimum denature enzymes by breaking bonds, altering the active site's shape, and rendering them inactive.

Temperatures above the optimum cause enzyme denaturation as bonds vibrate, break, and alter the active site's shape, rendering the enzyme inactive.

Front Explain why increasing the temperature up from the optimum decreases the rate of reaction abruptly.
Back Increasing temp up from optimum:
  • At higher temp, bonds holding enzyme protein structure together vibrate more and eventually strain and break
  • Breaking of bonds result in change in the precise tertiary structure of the protein
  • Enzyme has changed shape - denatured
  • Active site has changed shape and is no longer complementary to substrate - substrate cant fit - enzyme is no longer a functional catalyst


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