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A-Level Biology OCR A

Examples Non Competetive Inhibitors Enzyme State Describe Action Organophosphates

Organophosphates inhibit acetylcholinesterase causing nerve issues, while proton pump inhibitors reduce stomach acid by blocking a key enzyme.

Organophosphates inhibit acetylcholinesterase, affecting nerve impulses, and proton pump inhibitors reduce stomach acid by blocking a specific enzyme system.

Front State two examples of non-competetive inhibitors and describe their action.
Back Examples of non-competetive inhibitors:
  • Organophosphates (herbicides and insecticides) inhibit enzyme acetyl cholinesterase (responsible for nerve impulse transmission) - leads to muscle cramps, paralysis or death
  • Proton pump inhibitors (treat long-term indigestion) block enzyme system responsible for secreting H+ ions into stomach, reduces production of excess acid, preventing ulcers

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