Question

Draw a graph showing how substrate conc affects rate of an enzyme-controlled reaction if a comp or non comp inhibitor is present. Explain effect of these inhibitors on Vmax of an enzyme-controlled reaction.

Accepted Answer

Non-competetive inhibitors permanently lower the Vmax of a reaction, adding more substrate will not overcome effect of themCompetetive inhibitors do not lower the Vmax of a reaction, adding more substrate will result in more substrate than inhibitor and original Vmax will be reached

Front	Draw a graph showing how substrate conc affects rate of an enzyme-controlled reaction if a comp or non comp inhibitor is present. Explain effect of these inhibitors on V_max of an enzyme-controlled reaction.
Back	Non-competetive inhibitors permanently lower the V_max of a reaction, adding more substrate will not overcome effect of them Competetive inhibitors do not lower the V_maxof a reaction, adding more substrate will result in more substrate than inhibitor and original V_max will be reached

Substrate V Max Inhibitors Enzyme Controlled Comp Effect Lower