Question

State where G1 checkpoint occurs, what is checked at the checkpoint and what happens if cell passes/fails.

Accepted Answer

G1 checkpoint - at the end of G1 phase before entry into S phaseChecks: cell size, nutrients, growth factors, DNA dmgIf requirements satisfied - DNA replication beginsIf requirements not satisfied - cell enters G0

Front	State where G1 checkpoint occurs, what is checked at the checkpoint and what happens if cell passes/fails.
Back	G1 checkpoint - at the end of G1 phase before entry into S phase Checks: cell size, nutrients, growth factors, DNA dmg If requirements satisfied - DNA replication begins If requirements not satisfied - cell enters G0

G1 Checkpoint Cell Phase Dna Requirements Satisfied State