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O High Low Hb Draw Annotate Oxygen Dissociation

Increased CO2 shifts the oxygen dissociation curve to the right (decreasing hemoglobin's affinity for O2). This happens because H+ ions from carbonic acid formation compete with O2 for binding sites on hemoglobin, causing hemoglobin to release O2 more readily.

El aumento del CO2 desplaza la curva de disociación de oxígeno hacia la derecha (disminuyendo la afinidad de la hemoglobina por el O2). Esto ocurre porque los iones H+ de la formación de ácido carbónico compiten con el O2 por los sitios de unión de la hemoglobina, lo que provoca que la hemoglobina libere el O2 más fácilmente.

Front Draw and annotate oxygen dissociation curves to show the effect of partial pressure of CO2 on the shape of the curve.
Back

  • C - high CO2, low O2
  • A - low CO2 high O2
  • This happens bc H+ ions from carbonic acid compete with O2 to occupy Hb, decreasing affinity of Hb for O2
  • High CO2 therefore cause Hb to unload O2

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