In mammals, miRNA binds to target mRNA, often less specifically than siRNA, blocking translation and potentially leading to mRNA storage or degradation.
In mammals, miRNA binds to target mRNA, often less specifically than siRNA, blocking translation and potentially leading to mRNA storage or degradation.
| Front | miRNA in mammals |
|---|---|
| Back | miRNA isn't usually complementary to target mRNA since it is less specific than siRNA it may target more than one mRNA molecule Associates with proteins and binds to target mRNA in cytoplasm miRNA-protein complex physically blocks translation of target mRNA mRNA moved into processing body, can either be stored or degraded Can be returned and translated at another time |
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