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Mrna Target Mirna Mammals Complementary Specific Sirna Molecule

In mammals, miRNA binds to target mRNA, often less specifically than siRNA, blocking translation and potentially leading to mRNA storage or degradation.

In mammals, miRNA binds to target mRNA, often less specifically than siRNA, blocking translation and potentially leading to mRNA storage or degradation.

Front miRNA in mammals
Back miRNA isn't usually complementary to target mRNA
since it is less specific than siRNA it may target more than one mRNA molecule
Associates with proteins and binds to target mRNA in cytoplasm
miRNA-protein complex physically blocks translation of target mRNA
mRNA moved into processing body, can either be stored or degraded
Can be returned and translated at another time

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