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Sirna Mrna Proteins Target Base Sequence Fragments Method

Front Method of SiRNA (miRNA in plants)
Back mRNA transcribed
leaves nucleus for cytoplasm
Double stranded siRNA associates with several proteins and unwinds
A single strand binds to target mRNA
Base sequence of siRNA complementary to base sequence of target mRNA
proteins associated with siRNA cut mRNA into fragments so it can no longer be translated
Fragments move to processing body which degrades them
Similar process occurs with miRNA in plants

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