Acetylation of proto-oncogene histones increases transcriptional factor and RNA polymerase binding, boosting transcription and translation rates, resulting in excess protein production and uncontrolled cell division, leading to cancer.
- acetylation of histones - more binding of transcriptional factors to promoter - RNA polymerase stimulated to transcribe gene - rate of transcription increases - rate of translation increases - more protein produced - uncontrolled cell division occurs
| Front | How does acetylation of proto-oncogenes lead to cancer? |
|---|---|
| Back | - acetylation of histones - more binding of transcriptional factors to promoter - RNA polymerase stimulated to transcribe gene - rate of transcription increases - rate of translation increases - more protein produced - uncontrolled cell division occurs |
Tags: gene_expression
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