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Methylation Dna Tumour Suppressor Rate Decreases Genes Lead

Front How does methylation of DNA in tumour suppressor genes lead to cancer?
Back - methylation of DNA in promoter
- binding transcriptional factors inhibited
- RNA polymerase not stimulated to transcribe gene
- rate of transcription decreases
- rate of translation decreases
- tumour suppressor protein is not produced
- uncontrolled cell division occurs

Tags: gene_expression

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