In the late phase of allergen re-exposure in asthmatics, inflammation, particularly major basic protein from eosinophils, damages cells and perpetuates bronchoconstriction.
Bei Asthmatikern führt die erneute Exposition gegenüber einem Allergen zu einer IgE-vermittelten Aktivierung von Mastzellen. In der späten Phase dieser Reaktion schädigt die Entzündung, insbesondere das Hauptbasenprotein von Eosinophilen, die Zellen und hält die Bronchokonstriktion aufrecht.
| Front | In asthmatic individuals, reexposure to an allergen leads to an IgE-mediated activation of mast cells. What occurs in the late phase of this reaction? |
|---|---|
| Back | Inflammation, especially major basic protein derived from eosinophils, damages cells and perpetuates bronchoconstriction. |
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