The process of a normal enzyme reaction involves the formation of an enzyme-substrate complex according to enzyme-substrate specificity, where the active site undergoes conformational change for induced fit. This change destabilizes bonds in the substrate, lowering activation energy (Ea), allowing the substrate to be converted to product at an accelerated rate.
El proceso de una reacción enzimática normal implica la formación de un complejo enzima-sustrato según la especificidad enzima-sustrato, donde el sitio activo cambia de conformación para el encaje inducido. Este cambio desestabiliza los enlaces del sustrato, reduciendo la energía de activación (Ea), lo que permite que el sustrato se convierta en producto a una velocidad acelerada.
| Original | formation of enzyme-substrate complex according to enzyme-substrate specificity active site undergoes conformational change upon binding for induced fit conformational change destabilizes bonds in substrate, lowering Ea substrate is converted to product at accelerated rate |
|---|---|
| Title | process of a normal enzyme reaction |
| Settings | 1,1,0 | n,n,n,n |
| Text1 | formation of enzyme-substrate complex according to enzyme-substrate specificity ... ... ... |
| Text2 | formation of enzyme-substrate complex according to enzyme-substrate specificity active site undergoes conformational change upon binding for induced fit ... ... |
| Text3 | ... active site undergoes conformational change upon binding for induced fit conformational change destabilizes bonds in substrate, lowering Ea ... |
| Text4 | ... ... conformational change destabilizes bonds in substrate, lowering Ea substrate is converted to product at accelerated rate |
| Full | formation of enzyme-substrate complex according to enzyme-substrate specificity active site undergoes conformational change upon binding for induced fit conformational change destabilizes bonds in substrate, lowering Ea substrate is converted to product at accelerated rate |
Tags: 8_1_metabolism
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