This flashcard introduces CR3 (CD11b:CD18), a β2 integrin that functions as both an adhesion molecule and a complement receptor. CR3 binds to iC3b, a breakdown product of C3b found on bacteria, stimulating phagocytosis.
Bu flaş kart, hem yapışma molekülü hem de kompleman reseptörü olarak işlev gören bir β2 integrini olan CR3'ü (CD11b:CD18) tanıtmaktadır. Hücreleri yutmadan önce bakterilerin üzerinde oluşan bir C3b yıkım ürünü olan iC3b'ye bağlanan CR3, özellikle fagositozu uyarır.
| Front | A β2 integrin that acts both as an adhesion molecule and as a complement receptor. On phagocytes this β2 integrin binds iC3b, a breakdown product of C3b on pathogen surfaces, and stimulates phagocytosis |
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| Back | CR3 CD11b:CD18 |
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