This flashcard describes CR4 (CD11c:CD18) as a β2 integrin functioning as both an adhesion molecule and a complement receptor. On phagocytes, it binds to iC3b on pathogen surfaces, stimulating phagocytosis.
Questa flashcard descrive CR4 (CD11c:CD18) come una β2 integrina che agisce sia come molecola di adesione che come recettore del complemento. Sui fagociti, si lega a iC3b sulle superfici dei patogeni, stimolando la fagocitosi.
| Front | A β2 integrin that acts both as an adhesion molecule and as a complement receptor. On phagocytes this β2 integrin binds iC3b, a breakdown product of C3b on pathogen surfaces, and stimulates phagocytosis |
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| Back | CR4 CD11c:CD18 |
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