Chediak–Higashi syndrome is a defect in phagocytic cell function caused by a deficiency in a protein involved in intracellular vesicle fusion, impairing the killing of ingested bacteria.
El síndrome de Chediak-Higashi es un defecto en la función de las células fagocíticas causado por un defecto en una proteína implicada en la fusión de vesículas intracelulares, lo que dificulta la eliminación de bacterias ingeridas.
| Front | A defect in phagocytic cell function caused by a defect in a protein involved in intracellular vesicle fusion. Lysosomes fail to fuse properly with phagosomes, and killing of ingested bacteria is impaired |
|---|---|
| Back | Chediak–Higashi syndrome |
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