CD40 ligand deficiency is an immunodeficiency where little or no IgG, IgE, or IgA is produced, and IgM responses are also deficient due to a defect in CD40L preventing class switching.
La deficiencia del ligando CD40 es una inmunodeficiencia donde se produce poca o ninguna IgG, IgE o IgA, y las respuestas IgM también son deficientes debido a un defecto en CD40L que impide el cambio de clase.
| Front | An immunodeficiency disease in which little or no IgG, IgE, or IgA antibody is produced and even IgM responses are deficient, but serum IgM levels are normal to high. It is due to a defect in the gene encoding CD40L, which prevents class switching from occurring. Also known as X-linked hyper IgM syndrome |
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| Back | CD40 ligand deficiency |
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