Wiskott–Aldrich syndrome (WAS) is an immunodeficiency characterized by cytoskeletal defects due to mutations in WASp, leading to susceptibility to bacterial infections and defects in T-follicular helper cell interactions.
El síndrome de Wiskott-Aldrich (WAS) es una inmunodeficiencia caracterizada por defectos en el citoesqueleto celular debido a mutaciones en WASp, lo que causa susceptibilidad a infecciones bacterianas y defectos en interacciones de células T foliculares auxiliares.
| Front | An immunodeficiency disease characterized by defects in the cytoskeleton of cells due to a mutation in the protein WASp, which is involved in interactions with the actin cytoskeleton. Patients with this disease are highly susceptible to infections with pyogenic bacteria due to defects in T-follicular helper cell interactions with B cells |
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| Back | Wiskott–Aldrich syndrome WAS |
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