Transporters associated with antigen processing (TAP1, TAP2) are ATP-binding cassette proteins forming a heterodimeric complex in the ER membrane, transporting short peptides from the cytosol into the ER lumen for association with MHC class I molecules.
Los transportadores asociados al procesamiento de antígenos (TAP1, TAP2) son proteínas ABC que forman un complejo heterodimérico en la membrana del RE, transportando péptidos cortos del citosol al lumen del RE para su asociación con moléculas MHC clase I.
| Front | Transporters associated with antigen processing. ATP-binding cassette proteins that form a heterodimeric complex in the endoplasmic reticulum membrane, through which short peptides are transported from the cytosol into the lumen of the endoplasmic reticulum, where they associate with MHC class I molecules |
|---|---|
| Back | TAP1, TAP2 |
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