Cyclophilins are a family of prolylisomerases that affect protein folding and bind cyclosporine A to form a complex that associates with calcineurin, preventing its activation by calmodulin.
Cyclofilines zijn een familie van prolylisomerasen die eiwitvouwing beïnvloeden. Ze binden ook cyclosporine A en produceren een complex dat associeert met calcineurine, waardoor de activering ervan doorcalmoduline wordt voorkomen.
| Front | A family of prolylisomerases that affect protein folding, that also bind cyclosporin A to produce a complex that associates with calcineurin, preventing its activation by calmodulin |
|---|---|
| Back | cyclophilins |
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