FcεRI is the high affinity receptor for the Fc region of IgE, primarily expressed on mast cells and basophils, whose activation by multivalent antigen causes degranulation.
FcεRI es el receptor de alta afinidad para la región Fc de IgE, expresado principalmente en mastocitos y basófilos, cuya activación por antígenos multivalentes causa degranulación.
| Front | The high affinity receptor for the Fc region of IgE. Expressed primarily on the surface of mast cells and basophils. When multivalent antigen interacts with IgE that is bound to FcεRI and cross-links nearby receptors, it causes activation of the receptor-bearing cell |
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| Back | FcεRI |
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