Histamine is a vasoactive amine stored in mast cell granules, whose release by antigen-IgE binding causes local blood vessel dilation and smooth muscle contraction, contributing to allergic symptoms.
La histamina es una amina vasoactiva almacenada en los gránulos de los mastocitos, cuya liberación por el enlace antígeno-IgE causa dilatación de los vasos sanguíneos y contracción del músculo liso, contribuyendo a los síntomas alérgicos.
| Front | A vasoactive amine stored in mast-cell granules. Release of theis vasoactive amine by antigen binding to IgE antibodies bound to mast cells causes the dilation of local blood vessels and the contraction of smooth muscle, producing some of the symptoms of IgE-mediated allergic reactions |
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| Back | histamine |
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