Motheaten is a mutation in the SHP-1 protein phosphatase that impairs the function of some inhibitory receptors, such as Ly49, resulting in over-activation of various cells, including NK cells.
Motheaten es una mutación en la proteína fosfatasa SHP-1 que deteriora la función de algunos receptores inhibidores, como Ly49, lo que resulta en hiperactivación de varias células, incluidas las células NK.
| Front | A mutation in the SHP-1 protein phosphatase that impairs the function of some inhibitory receptors, such as Ly49, resulting in over-activation of various cells, including NK cells |
|---|---|
| Back | motheaten |
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